Dymista Nasal Spray (120 Sprays)

Hay Fever Doctor Service

Dymista Nasal Spray 137 Micrograms / 50 Micrograms Per Actuation - Azelastine hydrochloride/fluticasone propionate

Dymista Nasal Spray contains two active substances: azelastine hydrochloride and fluticasone propionate.

• Azelastine hydrochloride belongs to a group of medicines called antihistamines. Antihistamines work by preventing the effects of substances such as histamine that the body produces as part of an allergic reaction – thus reducing symptoms of allergic rhinitis.
• Fluticasone propionate belongs to a group of medicines called corticosteroids which reduces inflammation.

Combined, these ingredients are an effective treatment to reduce the common symptoms of hay fever. Dymista is used to relieve the symptoms of moderate to severe seasonal and perennial allergic rhinitis if the use of either intranasal antihistamine or corticosteroid alone is not considered sufficient.

Seasonal and perennial allergic rhinitis are allergic reactions to substances such as pollen (hayfever), house mites, moulds, dust or pets. Dymista Nasal Spray relieves the symptoms of allergies, for example: runny nose, post nasal drip, sneezing and itchy or blocked nose.

Suitable For Adults & Children Aged 12 Years & Older.

You can order Dymista spray online from our UK registered online pharmacy and doctor service. To see if you are suitable for this treatment, complete the online assessment and checkout. Our UK registered doctors will review the order and after approval pass the prescription to the Pharmacy team. We will then dispense and dispatch your order to your chosen address.

Effectiveness

Rhinolast is a widely used and effective rhinitis treatment however every patient can respond differently to medication. If you find that this medicine is not effective for you, you may want to try another alternative treatment.

Alternatives
Other treatments for hayfever and allergies are available at Rightdose. these include:

• Beconase Aqueous Nasal Spray
• Pirinase Hayfever Nasal Spray
• Rhinolast Nasal Spray
• Avamys Nasal Spray

A good self care guide and information for hay fever is available on the NHS website.

NHS - Hay fever

Hay fever is usually worse between late March and September, especially when it's warm, humid and windy.

What Can You Do To Ease Your Symptoms When The Pollen Count Is High? 

• Keep windows and doors shut as much as possible
• Wear wraparound sunglasses to stop pollen getting into your eyes
• Stay indoors whenever possible
• Put Vaseline around your nostrils to trap pollen
• Shower and change your clothes after you have been outside to wash pollen off
• Vacuum regularly and dust with a damp cloth
• Buy a pollen filter for the air vents in your car and a vacuum cleaner with a HEPA filter

How Do I Use Dymista Nasal Spray? 
Before using Dymista you will need to blow your nose to clear both nostrils, then slightly tilt your head back, and slowly exhale, using your free hand to close the nostril you are not spraying. Push down and on the pump and take 1 spray into your nostril, repeat for the other side. This can be done a maximum of twice daily, and you should start to see some effects within 30 to 60 minutes, but it can take on some occasions a few days to get the full benefit.

Can I Use Dymista Nasal Spray Long Term?
Dymista Nasal Spray can be used on a long term basis, if instructed to do so by your Doctor or Health professional, it is advised that you should only use it when required.

Can I Use Dymista Nasal Spray If I Am Pregnant Or Breastfeeding?
No. It is advised that you should not use Dymista Nasal Spray if you are pregnant or breastfeeding until you have spoken with your Doctor or Health professional.

Can I Take Dymista Nasal Spray With Alcohol?
Using Alcohol whilst taking Dymista Nasal Spray can increase your chances of suffering the side effects of the medication, however, if alcohol is used in moderation while taking Dymista there should be no issues.

Does Using Dymista Nasal Spray Cause Weight Gain?
There is no proof that using Dymista Nasal Sprays causes weight gain. If you think you are gaining weight using Dymista, it is advised that you speak to your Doctor or Health professional.

Like all medicines Dymista Nasal Spray can cause side effects, although not everybody gets them.

These effects include:
Very common side effects (These may affect more than 1 in 10 people):

• Nosebleed

Common side effects (These may affect up to 1 in 10 people):

• A bitter taste in your mouth, especially if you tilt your head backwards when you are using the nasal spray. This should go away if you have a soft drink a few minutes after using this medicine.
• Headache
• Unpleasant smell

Uncommon side effects (These may affect up to 1 in 100 people):

• Slight irritation of the inside of the nose. This can cause mild stinging, itching or sneezing.
• Nasal dryness, cough, dry throat or throat irritation.

Seek immediate medical help if you have any of the following symptoms:

• Swelling of face, lips, tongue or throat which may cause difficulty in swallowing/breathing and a sudden onset of skin rash. This could be signs of a severe allergic reaction. Please note: This is very rare.

Side effects with unknown frequency (frequency cannot be estimated from the available data)

• Blurred vision
• Sores in the nose

Systemic side effects (side effects concerning the whole body) may occur when this medicine is used at high doses for a long time. These effects are much less likely to occur if you use a corticosteroid nasal spray than if you take corticosteroids by mouth. These effects may vary in individual patients and between different corticosteroid preparations.

Nasal corticosteroids can affect the normal production of hormones in your body, particularly if you use high doses for a long time.

In children and adolescents this side effect can cause them to grow more slowly than others.

In rare cases a reduction of the bone density (osteoporosis) was observed, if nasal corticosteroids were administered long-term.

For a full list of side effects, please read the Patient Information Leaflet.

If you get any side effects, talk to your doctor, our Rightdose pharmacists or nurse. This includes any possible side effects not listed in this leaflet.

You can help to make medicines safer by reporting any side-effects to the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.

Patient Information Leaflet Dymista Nasal Spray (120 Sprays)

Children
This medicine is not recommended for children under 12 years.

Other medicines and Dymista Nasal Spray
Tell your doctor or pharmacist, if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. Some medicines may increase the effects of Dymista Nasal Spray and your doctor may wish to monitor you carefully if you are taking these medicines (including some medicines for HIV:
ritonavir, cobicistat and medicines for the treatment of fungal infections: ketoconazole).

Pregnancy and breastfeeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using Dymista Nasal Spray.

Driving and using machines
Dymista Nasal Spray has minor influence on the ability to drive and use machines. Very rarely, you may experience fatigue or dizziness due to the disease itself or when using Dymista Nasal Spray. In these cases, do not drive or operate machinery. Please be aware that drinking alcohol may enhance these effects.

Dymista Nasal Spray contains benzalkonium chloride
This medicine contains 14 micrograms of benzalkonium chloride in each spray, which is equivalent to 0.014 mg / 0.14 g. Benzalkonium chloride may cause irritation or swelling inside the nose, especially if used for a long time.

Tell your doctor or pharmacist if you feel discomfort when using the spray.

How to store Dymista Nasal Spray

• Do not use this medicine after the expiry date which is stated on the bottle label and the outer carton after “EXP”. The expiry date refers to the last day of that month.
• Do not refrigerate or freeze.
• Dispose of any unused medicine 6 months after you first open the nasal spray.
• Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Keep this medicine out of the sight and reach of children.

How to use Dymista Nasal Spray

Always use Dymista Nasal Spray exactly as your doctor has told you. Check with your
doctor or pharmacist, if you are not sure. It is essential to use Dymista Nasal Spray regularly to gain the full therapeutic benefit.

Contact with the eyes should be avoided.

Adults and adolescents (12 years and above). This medicine is not recommended for children under 12 years.

• The recommended dose is one spray into each nostril in the morning and evening.

Directions:

For nasal use only.

Preparing the spray

1. Shake the bottle gently for 5 seconds by tilting it upwards and downwards and then remove the protective cap.
2. The first time the nasal spray is used, you must prime the pump by squirting it into the air.
3. Prime the pump by putting two fingers on either side of the spray pump and place your thumb on the bottom of the bottle.
4. Press down and release the pump 6 times until a fine mist appears.
5. Now your pump is primed and ready to use.

If the nasal spray has not been used for more than 7 days, you will need to re-prime the pump once by pressing down and releasing the pump.

Follow these steps:

1. Shake the bottle gently for 5 seconds by tilting it upwards and downwards and then
   remove the protective cap.
2. Blow your nose to clear your nostrils.
3. Keep your head tilted downwards towards your toes. Do not tilt your head backwards.
4. Hold the bottle upright and carefully insert the spray tip into one nostril.
5. Close the other nostril with your finger, rapidly press down once and sniff gently at the same time.
6. Breathe out through your mouth.
7. Repeat in your other nostril.
8. Breathe in gently, and do not tilt your head back after dosing. This will stop the medicine going into your throat and causing an unpleasant taste.
9. After each use, wipe the spray tip with a clean tissue or cloth and then replace the protective cap.
10. Do not prick the nozzle in case spray is not obtained.

Clean the actuator with water after each use.

Duration of treatment
Dymista Nasal Spray is suitable for long-term use. The duration of treatment should correspond to the period of experiencing allergy symptoms.

It is important that you take your dose as advised by your doctor. You should use only as much as your doctor recommends.

If you use more Dymista Nasal Spray than you should
If you spray too much of this medicine into your nose you are unlikely to have any problems. If you are worried or if you have used doses higher than recommended over a long period, contact your doctor.

If anyone, especially a child, accidentally drinks Dymista Nasal Spray, contact your doctor or nearest hospital casualty department as soon as possible.

If you forget to use Dymista Nasal Spray
Use your nasal spray as soon as you remember, then take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.

If you stop using Dymista Nasal Spray
Do not stop using Dymista Nasal Spray without asking your doctor, because this puts the success of the treatment at risk.

Please see the STEP-BY-STEP GUIDE TO USING THE NASAL SPRAY on your Patient Information Leaflet.

If you have any further questions on the use of this medicine, or if you have any discomfort using the nasal spray ask your doctor or pharmacist or nurse.

Do not use Dymista Nasal Spray:

If you are allergic to azelastine hydrochloride or fluticasone propionate or any of the other ingredients of this medicine.

Warnings and precautions
Talk to your doctor or pharmacist before using Dymista Nasal Spray if:

• You had a recent operation on your nose.
• You have an infection in your nose. Infections of the nasal airways should be treated with antibacterial or antifungal medication. If you are given medication for an infection in your nose you can continue to use Dymista Nasal Spray to treat your allergies.
• You have tuberculosis or an untreated infection.
• You have a change in vision or a history of increased ocular pressure, glaucoma and/or cataracts. If this applies to you, you will be closely monitored whilst using Dymista Nasal Spray.
• You suffer from impaired adrenal function. Care must be taken when transferring from systemic steroid treatment to Dymista Nasal Spray.
• You suffer from a severe liver disease. Your risk of suffering from systemic side effects is increased. In these cases your doctor will decide whether you can use Dymista Nasal Spray.

Taking nasal corticosteroids such as Dymista may when taken for a long time cause children and adolescents to grow more slowly. The doctor will check your child’s height regularly, and make sure he or she is taking the lowest possible effective dose.

Contact your doctor if you experience blurred vision or other visual disturbances.

If you are unsure whether the above applies to you, talk to your doctor or pharmacist before using Dymista Nasal Spray.

What Dymista Nasal Spray contains

The active substances are: azelastine hydrochloride and fluticasone propionate. Each g of suspension contains 1000 micrograms azelastine hydrochloride and 365 micrograms fluticasone propionate.

Each actuation (0.14 g) delivers 137 micrograms azelastine hydrochloride (= 125 micrograms azelastine) and 50 micrograms fluticasone propionate.

The other ingredients are: Disodium edetate, glycerol, microcrystalline cellulose, carmellose sodium, polysorbate 80, benzalkonium chloride , phenylethyl alcohol and purified water.

What Dymista Nasal Spray looks like and contents of the pack
Dymista Nasal Spray is a white, homogenous suspension.
Dymista Nasal Spray comes in an amber coloured glass bottle fitted with a spray pump, applicator and a protective cap.
The 10 ml bottle contains 6.4 g nasal spray, suspension (at least 28 actuations). The 25 ml bottle contains 23 g nasal spray, suspension (at least 120 actuations).

Dymista Nasal Spray is presented in:
Packs containing 1 bottle with 6.4 g nasal spray, suspension
Packs containing 1 bottle with 23 g nasal spray, suspension
Multipacks comprising 10 bottles, each containing 6.4 g nasal spray, suspension
Multipacks comprising 3 bottles, each containing 23 g nasal spray, suspension.

Not all pack sizes may be marketed.